Autoimmune Disease: When Your Body Gets Confused
- Dr. Joshua Beaudry
- 1 day ago
- 6 min read

Fatigue. Brain fog. Poor sleep. Digestive problems. Joint pain. Headaches. Inflammation.
These are symptoms we hear about every day. Some people experiencing them have already been diagnosed with an autoimmune condition. Others simply know they don't feel like themselves and want to understand why.
One important piece of the puzzle is that your immune system does not work by itself. Your brain, nervous system, hormones, digestive system, and immune system are constantly communicating.
Understanding those connections can help you look at your health from a much bigger perspective.
What Is Autoimmune Disease?
Your Immune System Is Designed to Protect You
Think of your immune system as your body's security system.
Its job is to recognize what belongs in your body and what doesn't. When it identifies something potentially harmful, it responds to help protect you.
With autoimmune disease, that process becomes disrupted. The immune system can lose some of its ability to properly distinguish between the body's own tissues and things that don't belong.
There are many different autoimmune diseases, including:
Hashimoto's thyroiditis
Rheumatoid arthritis
Lupus
Multiple sclerosis
Type 1 diabetes
Celiac disease
Crohn's disease
Ulcerative colitis
Psoriasis
Autoimmune disease is complex, and there usually isn't one single cause. Genetics can play a role, but infections, environmental exposures, nutrition, stress, sleep, gut health, hormones, and other factors may also influence immune function.
Common Autoimmune Symptoms: Your Symptoms Are Information
What Is Your Body Trying to Tell You?
One of the biggest challenges is that people can experience symptoms for months or even years without understanding what those symptoms may be telling them.
Common complaints can include:
Persistent fatigue
Brain fog or difficulty concentrating
Joint or muscle discomfort
Digestive problems
Poor or disrupted sleep
Skin changes
Headaches
Changes in mood
Ongoing inflammation
Having one or more of these symptoms does not automatically mean you have an autoimmune disease. There are many possible causes, which is why proper evaluation is important.
But persistent symptoms shouldn't simply be ignored.
Instead of only asking:
"How do I get rid of this symptom?"
Consider also asking:
"Why might my body be producing this symptom?"
That question can change the way you approach your health.
The Brain, Nervous System, and Immune System Connection
Your Brain and Immune System Are Constantly Communicating
Your brain isn't separate from your immune system.
It is constantly receiving information about what's happening throughout your body and sending signals back to help regulate your internal environment.
One major part of this communication involves the autonomic nervous system.
The sympathetic nervous system helps your body respond when you need to be alert, active, or prepared to deal with a threat. This is commonly associated with the "fight-or-flight" response.
The parasympathetic nervous system is heavily involved in rest, digestion, recovery, and restoration.
The vagus nerve is one important communication pathway connecting the brain with organs throughout the body and is involved in regulating many automatic processes.
What Is the HPA Axis?
Another important system is the hypothalamic-pituitary-adrenal axis, or HPA axis.
When your brain perceives a threat, the hypothalamus communicates with the pituitary gland. The pituitary then communicates with the adrenal glands, which release hormones including cortisol.
Cortisol often gets a bad reputation, but your body needs it. It plays important roles in:
Energy regulation
Metabolism
Blood pressure
The stress response
Immune activity
The issue isn't simply having cortisol. Problems can arise when the systems responsible for regulating stress, recovery, and inflammation are repeatedly challenged or become dysregulated.
Inflammation Can Affect the Brain Too
The Brain-Immune Connection Goes Both Ways
The brain influences the immune system, but the immune system also communicates back to the brain.
When the immune system becomes activated, immune cells can release signaling molecules called cytokines.
These signals can influence the brain and may contribute to symptoms such as fatigue, changes in sleep or appetite, difficulty concentrating, and the general feeling of being unwell that often accompanies illness.
So the relationship isn't simply:
Brain → Immune System
It's an ongoing conversation:
Brain ↔ Nervous System ↔ Hormones ↔ Immune System
That's why looking at only one system may not always tell the entire story.
Chronic Stress and Autoimmune Health
Stress Isn't "Just in Your Head"
Think about what happens when you're under significant stress.
Your heart rate may increase. Your breathing changes. Your muscles tighten. Your digestion can change. You may have difficulty sleeping.
Nothing necessarily has to physically happen to you for your body to respond. Your brain can perceive a threat and activate a very real physiological stress response.
Work pressure, financial concerns, relationship problems, lack of sleep, injury, illness, or emotional stress can all influence the systems involved in your body's stress response.
This doesn't mean that stress causes autoimmune disease. Autoimmune conditions are far more complicated than that.
It does mean that chronic stress can affect sleep, digestion, behavior, hormones, and other systems involved in maintaining overall health and immune regulation.
Gut Health and the Immune System
Why the Gut-Brain-Immune Connection Matters
Your gastrointestinal tract is another major part of the conversation.
The digestive system isn't simply a tube that processes food. It is a major interface between the outside world and your internal environment.
Every day, food, bacteria, and other substances interact with the intestinal lining and immune system.
The gut microbiome—the community of microorganisms living within your digestive tract—also interacts with your immune and metabolic systems.
That's why when we're looking at overall immune health, it's helpful to look beyond the immune system itself.
Ask questions such as:
How are you eating?
How are you sleeping?
How much are you moving?
How much stress are you under?
How is your digestion?
What changed before your symptoms began?
Sometimes these questions reveal patterns that looking at an individual symptom cannot.
Understanding the Stress, Sleep, and Inflammation Cycle
How One Problem Can Feed Into Another
Your body's systems don't operate independently.
For example:
Stress can disrupt sleep.
Poor sleep can make stress more difficult to manage.
Stress and insufficient sleep can influence the body's regulation of inflammatory processes.
Inflammatory signals can affect the brain and contribute to fatigue, brain fog, poor sleep, and feeling unwell.
Feeling unwell can then create additional stress.
And the cycle can continue.
Again, this does not mean stress or poor sleep alone causes autoimmune disease. It illustrates why the connection between the brain, nervous system, hormones, gut, immune system, and lifestyle matters.
How to Support Your Brain, Nervous System, and Immune Health
Start With the Foundations
Whether or not you have an autoimmune diagnosis, there are foundational areas of health worth paying attention to.
Prioritize sleep. Aim for a consistent sleep schedule and give your body adequate time for rest and recovery.
Eat nutrient-dense foods. Focus on quality protein, vegetables, fiber, healthy fats, and foods that work well for your individual needs.
Move your body regularly. Exercise and movement influence cardiovascular health, metabolism, brain function, mood, sleep, and overall well-being.
Give your nervous system opportunities to recover. Stress management doesn't mean pretending everything is fine. It means regularly creating opportunities for your body to shift out of a constant state of alertness.
Look for patterns. Think about what was happening around the time your symptoms began or changed.
Was there an illness or infection? A major stressful event? A change in diet? A new medication? An injury? Poor sleep? A major lifestyle change or environmental exposure?
Finding a connection doesn't necessarily mean you've identified the cause. But it may help you and your healthcare providers ask better questions.
Your Body Isn't Your Enemy
Learn to Listen to What Your Body Is Telling You
One of the biggest mindset shifts we can make is to stop thinking of the body as though it's deliberately working against us.
Your body is constantly attempting to respond, adapt, protect you, and maintain balance.
Sometimes those systems become dysregulated.
When that happens, managing symptoms may be important, but understanding the bigger picture can be valuable too.
If you're experiencing persistent fatigue, brain fog, digestive problems, joint pain, inflammation, poor sleep, or other unexplained symptoms, don't simply assume feeling bad is something you have to live with.
Get evaluated. Ask questions. Look for patterns.
Most importantly, learn to listen to the information your body is giving you.
Your symptoms are information. The goal isn't to become afraid of your body. The goal is to understand it better.
Take the Next Step Toward Understanding Your Health
If you're ready to take the next step, contact us today to set up your initial examination or join us at an upcoming workshop.
Life Springs Family Chiropractic – Denver, CO
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